Альверин снимает спазм путём релаксации гладкой мускулатуры кишечника 1
СХЕМА ПРИЕМА
Курс лечения определяет врач индивидуально.
По 1 капсуле 2-3 раза в сутки до еды1
Литература
Инструкция по медицинскому применению лекарственного средства Метеоспазмил.
T. Wittmann, L. Paradowsky. Clinical trial: the efficacy of alverine citrate⁄simeticone combination on abdominal pain⁄discomfort in irritable bowel syndrome- a randomized, double-blind, placebo-controlled study. Aliment Pharmacol Ther 31, 615–624. 2010 Blackwell Publishing Ltd. doi:10.1111/j.1365-2036.2009.04216.
Douglas A. Drossman. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV. Gastroenterology 2016; Vol. 150, No. 6. 1262–1279
Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype. Anne-Marie Coelho, Luc Jacob, Jean Fioramonti and Lionel Bueno. Journal of Pharmacy and Pharmacology 2010; 53: 1419—1426.
Curtis J. Ingold; Hossein Akhondi. Simethicone. StatPearls [Internet]. Treasure Island (FL): Stat Pearls Publishing. PMID: 32310457 Bookshelf ID: NBK555997. Last Update: July 4, 2022.
Barraza-Ortiz D.A. Pérez-López N. at al. Combination of a probiotic and an antispasmodic increases quality of life and reduces symptoms in patients with irritable bowel syndrome: a pilot study -Digestive Diseases Vol. 39, No. 3, 2021 Issue release date: May 2021